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On the mechanism of action of ribonucleases: dinucleotide cleavage catalyzed by imidazole and Zn2+.

Cyclization/cleavage of the 2-(p-nitrophenyl) phosphate ester of propylene glycol is catalyzed by imidazole and, much more effectively, by Zn2+ with imidazole. In the latter case, the mechanism involves simultaneous Lewis acid/base catalysis. Similar Zn2+ and imidazole catalysis of cyclization/cleav...

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Bibliográfalaš dieđut
Publikašuvnnas:Proc Natl Acad Sci U S A
Váldodahkkit: Breslow, R, Huang, D L, Anslyn, E
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: National Academy of Sciences 1989
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286781/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2467290/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.6.1746
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