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An integrated machine learning approach for predicting DosR-regulated genes in Mycobacterium tuberculosis

BACKGROUND: DosR is an important regulator of the response to stress such as limited oxygen availability in Mycobacterium tuberculosis. Time course gene expression data enable us to dissect this response on the gene regulatory level. The mRNA expression profile of a regulator, however, is not necess...

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Autori principali: Zhang, Yi, Hatch, Kim A, Bacon, Joanna, Wernisch, Lorenz
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867773/
https://ncbi.nlm.nih.gov/pubmed/20356371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-37
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