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Three-dimensional distribution of transient interactions in the nuclear pore complex obtained from single-molecule snapshots

The translocation of large macromolecules through the nuclear pore complex (NPC) of eukaryotic cells is hindered by the phenylalanine-glycine (FG) nucleoporin (Nup) barrier unless molecules are chaperoned by transport receptors. The precise mechanism of facilitated translocation remains unclear due...

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Bibliographic Details
Main Authors: Ma, Jiong, Yang, Weidong
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867735/
https://ncbi.nlm.nih.gov/pubmed/20368455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908269107
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