Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)

Advanced age-related macular degeneration (AMD) is the leading cause of late onset blindness. We present results of a genome-wide association study of 979 advanced AMD cases and 1,709 controls using the Affymetrix 6.0 platform with replication in seven additional cohorts (totaling 5,789 unrelated ca...

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Autors principals: Neale, Benjamin M., Fagerness, Jesen, Reynolds, Robyn, Sobrin, Lucia, Parker, Margaret, Raychaudhuri, Soumya, Tan, Perciliz L., Oh, Edwin C., Merriam, Joanna E., Souied, Eric, Bernstein, Paul S., Li, Binxing, Frederick, Jeanne M., Zhang, Kang, Brantley, Milam A., Lee, Aaron Y., Zack, Donald J., Campochiaro, Betsy, Campochiaro, Peter, Ripke, Stephan, Smith, R. Theodore, Barile, Gaetano R., Katsanis, Nicholas, Allikmets, Rando, Daly, Mark J., Seddon, Johanna M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867697/
https://ncbi.nlm.nih.gov/pubmed/20385826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912019107
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