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Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)

Advanced age-related macular degeneration (AMD) is the leading cause of late onset blindness. We present results of a genome-wide association study of 979 advanced AMD cases and 1,709 controls using the Affymetrix 6.0 platform with replication in seven additional cohorts (totaling 5,789 unrelated ca...

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Detalhes bibliográficos
Main Authors: Neale, Benjamin M., Fagerness, Jesen, Reynolds, Robyn, Sobrin, Lucia, Parker, Margaret, Raychaudhuri, Soumya, Tan, Perciliz L., Oh, Edwin C., Merriam, Joanna E., Souied, Eric, Bernstein, Paul S., Li, Binxing, Frederick, Jeanne M., Zhang, Kang, Brantley, Milam A., Lee, Aaron Y., Zack, Donald J., Campochiaro, Betsy, Campochiaro, Peter, Ripke, Stephan, Smith, R. Theodore, Barile, Gaetano R., Katsanis, Nicholas, Allikmets, Rando, Daly, Mark J., Seddon, Johanna M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867697/
https://ncbi.nlm.nih.gov/pubmed/20385826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912019107
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