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A Transmural Gradient in the Cardiac Na/K Pump Generates a Transmural Gradient in Na/Ca Exchange

We previously demonstrated a transmural gradient in Na/K pump current (I(P)) and [Na(+)](i), with the highest maximum I(P) and lowest [Na(+)](i) in epicardium. The present study examines the relationship between the transmural gradient in I(P) and Na/Ca exchange (NCX). Myocytes were isolated from ca...

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Hlavní autoři: Wang, Wei, Gao, Junyuan, Entcheva, Emilia, Cohen, Ira S., Gordon, Chris, Mathias, Richard T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867674/
https://ncbi.nlm.nih.gov/pubmed/20130849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-010-9224-y
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