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A Penalized Mixture Model Approach in Genotype/Phenotype Association Analysis for Quantitative Phenotypes

A mixture normal model has been developed to partition genotypes in predicting quantitative phenotypes. Its estimation and inference are performed through an EM algorithm. This approach can conduct simultaneous genotype clustering and hypothesis testing. It is a valuable method for predicting the di...

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Bibliografiske detaljer
Main Authors: Li, Lang, Borges, Silvana, Jason, Robarge D., Shen, Changyu, Desta, Zeruesenay, Flockhart, David
Format: Artigo
Sprog:Inglês
Udgivet: Libertas Academica 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867634/
https://ncbi.nlm.nih.gov/pubmed/20467479
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