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A Penalized Mixture Model Approach in Genotype/Phenotype Association Analysis for Quantitative Phenotypes

A mixture normal model has been developed to partition genotypes in predicting quantitative phenotypes. Its estimation and inference are performed through an EM algorithm. This approach can conduct simultaneous genotype clustering and hypothesis testing. It is a valuable method for predicting the di...

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Detalhes bibliográficos
Main Authors: Li, Lang, Borges, Silvana, Jason, Robarge D., Shen, Changyu, Desta, Zeruesenay, Flockhart, David
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867634/
https://ncbi.nlm.nih.gov/pubmed/20467479
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