Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds

The broadly neutralizing antibody 2G12 recognizes a conserved cluster of high mannose glycans on the surface envelope spike of HIV suggesting that the “glycan shield” defense of the virus can be breached and may, under the right circumstances, serve as a vaccine target. In an attempt to recreate fea...

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Main Authors: Astronomo, Rena D., Kaltgrad, Eiton, Udit, Andrew K., Wang, Sheng-Kai, Doores, Katie J., Huang, Cheng-Yuan, Pantophlet, Ralph, Paulson, James C., Wong, Chi-Huey, Finn, M.G., Burton, Dennis R.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867452/
https://ncbi.nlm.nih.gov/pubmed/20416507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.03.012
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