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Sex-related resistance to myocardial ischemia-reperfusion injury is associated with high constitutive ARC expression

The female sex has been associated with improved myocardial salvage after ischemia and reperfusion (I/R). Estrogen, specifically 17β-estradiol, has been demonstrated to mediate this phenomenon by limiting cardiomyocyte apoptosis. We sought to quantitatively assess the effect of sex, ovarian hormone...

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Detalhes bibliográficos
Main Authors: Bouma, Wobbe, Noma, Mio, Kanemoto, Shinya, Matsubara, Muneaki, Leshnower, Bradley G., Hinmon, Robin, Gorman, Joseph H., Gorman, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867440/
https://ncbi.nlm.nih.gov/pubmed/20173041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01021.2009
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