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Putative anion transporter-1 (Pat-1, Slc26a6) contributes to intracellular pH regulation during H(+)-dipeptide transport in duodenal villous epithelium

The majority of dietary amino acids are absorbed via the H(+)-di-/tripeptide transporter Pept1 of the small intestine. Proton influx via Pept1 requires maintenance of intracellular pH (pH(i)) to sustain the driving force for peptide absorption. The apical membrane Na(+)/H(+) exchanger Nhe3 plays a m...

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Detalhes bibliográficos
Main Authors: Simpson, Janet E., Walker, Nancy M., Supuran, Claudiu T., Soleimani, Manoocher, Clarke, Lane L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867431/
https://ncbi.nlm.nih.gov/pubmed/20150244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00293.2009
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