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Cyclic AMP stimulates Mrp2 translocation by activating p38α MAPK in hepatic cells

Cyclic AMP (cAMP) induces translocation of multidrug resistant protein 2 (Mrp2) to the canalicular membrane and activates p38 MAPK in rat hepatocytes. In this study, we tested the hypothesis that cAMP-induced Mrp2 translocation may be mediated via p38 MAPK. Studies were conducted in rat hepatocytes...

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Main Authors: Schonhoff, Christopher M., Webster, Cynthia R. L., Anwer, M. Sawkat
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867428/
https://ncbi.nlm.nih.gov/pubmed/20203059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00506.2009
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