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Muscarinic receptor-mediated bronchoconstriction is coupled to caveolae in murine airways

Cholinergic bronchoconstriction is mediated by M(2) and M(3) muscarinic receptors (MR). In heart and urinary bladder, MR are linked to caveolin-1 or -3, the structural proteins of caveolae. Caveolae are cholesterol-rich, omega-shaped invaginations of the plasma membrane. They provide a scaffold for...

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Main Authors: Schlenz, Heike, Kummer, Wolfgang, Jositsch, Gitte, Wess, Jürgen, Krasteva, Gabriela
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867404/
https://ncbi.nlm.nih.gov/pubmed/20023174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00261.2009
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