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Bleomycin induces the extrinsic apoptotic pathway in pulmonary endothelial cells
Bleomycin, a chemotherapeutic agent, can cause pulmonary fibrosis in humans and is commonly used to induce experimental pulmonary fibrosis in rodents. In cell culture, bleomycin causes single- and double-stranded DNA breaks and produces reactive oxidative species, both of which require iron (Fe(2+))...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867402/ https://ncbi.nlm.nih.gov/pubmed/20154224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00322.2009 |
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