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Origins of Resistance to the HIVgp41 Viral Entry Inhibitor T20
The peptide T20, which targets the HIV protein gp41, represents the first approved member in the HIV drug class known as membrane fusion inhibitors. However, mechanisms which lead to resistance through clinical use of T20 are not well-understood because the structure of the bound complex remains und...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867330/ https://ncbi.nlm.nih.gov/pubmed/20230061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901915g |
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