Tbx1 regulates Vegfr3 and is required for lymphatic vessel development

Lymphatic dysfunction causes several human diseases, and tumor lymphangiogenesis is implicated in cancer spreading. TBX1 is the major gene for DiGeorge syndrome, which is associated with multiple congenital anomalies. Mutation of Tbx1 in mice recapitulates the human disease phenotype. In this study,...

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Hlavní autoři: Chen, Li, Mupo, Annalisa, Huynh, Tuong, Cioffi, Sara, Woods, Matthew, Jin, Chengliu, McKeehan, Wallace, Thompson-Snipes, LuAnn, Baldini, Antonio, Illingworth, Elizabeth
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2010
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867300/
https://ncbi.nlm.nih.gov/pubmed/20439995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200912037
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