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Wild-type BRCA1, but not Mutated BRCA1, Regulates the Expression of the Nuclear Form of β-catenin
BRCA1 is an essential caretaker protein in the surveillance of DNA damage, is mutated in about 50% of all hereditary breast cancer cases and its expression is frequently decreased in sporadic breast cancer. β-catenin is a multifunctional protein that forms adhesion complex with E-cadherins, α-cateni...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867250/ https://ncbi.nlm.nih.gov/pubmed/20215423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0403 |
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