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Gold-catalyzed efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation

A surprisingly efficient synthesis of azepan-4-ones via two-step [5 + 2] annulation is developed. This reaction involves a key gold catalysis and shows generally high regioselectivities and good to excellent diastereoselectivities.

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Detalhes bibliográficos
Main Authors: Cui, Li, Ye, Longwu, Zhang, Liming
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867248/
https://ncbi.nlm.nih.gov/pubmed/20442898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c001314e
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