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The selective macroautophagic degradation of aggregated proteins requires the phosphatidylinositol 3-phosphate binding protein Alfy

There is growing evidence that macroautophagic cargo is not limited to bulk cytosol in response to starvation, and can occur selectively for substrates including aggregated proteins. It remains unclear, however, if starvation-induced and selective macroautophagy share identical adapter molecules to...

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Dettagli Bibliografici
Autori principali: Filimonenko, Maria, Isakson, Pauline, Finley, Kim D., Anderson, Monique, Melia, Thomas J., Jeong, Hyun, Bartlett, Bryan J., Myers, Katherine M., Birkeland, Hanne C.G., Lamark, Trond, Krainc, Dimitri, Brech, Andreas, Stenmark, Harald, Simonsen, Anne, Yamamoto, Ai
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867245/
https://ncbi.nlm.nih.gov/pubmed/20417604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.04.007
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