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Gel mobilities of linking-number topoisomers and their dependence on DNA helical repeat and elasticity

Agarose-gel electrophoresis has been used for more than thirty years to characterize the linking-number (Lk) distribution of closed-circular DNA molecules. Although the physical basis of this technique remains poorly understood, the gel-electrophoretic behavior of covalently closed DNAs has been use...

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Bibliographische Detailangaben
Hauptverfasser: Vetcher, Alexandre A., McEwen, Abbye E., Abujarour, Ramzey, Hanke, Andreas, Levene, Stephen D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867096/
https://ncbi.nlm.nih.gov/pubmed/20346570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2010.02.016
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