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Functional and structural characterization of DR_0079 from Deinococcus radiodurans, a novel Nudix hydrolase with a preference for cytosine (deoxy)ribonucleoside 5’-di- and triphosphates

The genome of the extremely radiation resistant bacterium Deinococcus radiodurans encodes 21 Nudix hydrolases of which only two have been characterized in detail. Here we report the activity and crystal structure for DR_0079, the first Nudix hydrolase observed to have a marked preference for cytosin...

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Detalhes bibliográficos
Main Authors: Buchko, Garry W., Litvinova, Olga, Robinson, Howard, Yakunin, Alexander F., Kennedy, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867059/
https://ncbi.nlm.nih.gov/pubmed/18512963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800099d
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