The adapter protein Nck: Role of individual SH3 and SH2 binding modules for protein interactions in T lymphocytes

Nck is a ubiquitously expressed, primarily cytosolic adapter protein consisting of one SH2 domain and three SH3 domains. It links receptor and nonreceptor tyrosine kinases to actin cytoskeleton reorganizing proteins. In T lymphocytes, Nck is a crucial component of signaling pathways for T cell activ...

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Main Authors: Lettau, Marcus, Pieper, Jennifer, Gerneth, Alyn, Lengl-Janßen, Beate, Voss, Matthias, Linkermann, Andreas, Schmidt, Hendrik, Gelhaus, Christoph, Leippe, Matthias, Kabelitz, Dieter, Janssen, Ottmar
Formato: Artigo
Idioma:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867007/
https://ncbi.nlm.nih.gov/pubmed/20082308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.334
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