Activation of Hsp90/NOS and increased NO generation does not impair mitochondrial respiratory chain by competitive binding at cytochrome C Oxidase in low oxygen concentrations

Nitric oxide (NO) is known to regulate mitochondrial respiration, especially during metabolic stress and disease, by nitrosation of the mitochondrial electron transport chain (ETC) complexes (irreversible) and by a competitive binding at O(2) binding site of cytochrome c oxidase (CcO) in complex IV...

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Detalhes bibliográficos
Main Authors: Presley, Tennille, Vedam, Kaushik, Liu, Xiaoping, Zweier, Jay L., Ilangovan, Govindasamy
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2009
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866951/
https://ncbi.nlm.nih.gov/pubmed/19412660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-009-0114-0
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