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Molecular and cellular responses of islets during perturbations of glucose homeostasis determined by in situ hybridization histochemistry.

We have evaluated in situ hybridization histochemistry as a means of estimating simultaneously the level of prohormone mRNA and the dimensions of rat pancreatic islets. Localization of the 27-mer 32P-labeled oligonucleotide probes for rat proinsulin I, glucagon, and prosomatostatin I corresponded wi...

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Detalhes bibliográficos
Main Authors: Chen, L, Komiya, I, Inman, L, McCorkle, K, Alam, T, Unger, R H
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC286691/
https://ncbi.nlm.nih.gov/pubmed/2645581
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