Loss of insulin response to glucose but not arginine during the development of autoimmune diabetes in BB/W rats: relationships to islet volume and glucose transport rate.

The insulin and glucagon responses to 10 mM glucose and 10 mM arginine were studied in pancreata isolated from nondiabetic diabetes-prone and diabetes-resistant BB/W rats at 60, 80, and 140 days of age and in diabetic BB/W rats on the 1st and 14th days of their diabetes. In the former group the insu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tominaga, M, Komiya, I, Johnson, J H, Inman, L, Alam, T, Moltz, J, Crider, B, Stefan, Y, Baetens, D, McCorkle, K
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387218/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3540950/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.24.9749
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