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Formation of Covalently Bound Protein Adducts from the Cytotoxicant Naphthalene in Nasal Epithelium: Species Comparisons

BACKGROUND: Naphthalene is a volatile hydrocarbon that causes dose-, species-, and cell type–dependent cytotoxicity after acute exposure and hyperplasia/neoplasia after lifetime exposures in rodents. Toxicity depends on metabolic activation, and reactive metabolite binding correlates with tissue and...

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Sonraí Bibleagrafaíochta
Main Authors: DeStefano-Shields, Christina, Morin, Dexter, Buckpitt, Alan
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Institute of Environmental Health Sciences 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866680/
https://ncbi.nlm.nih.gov/pubmed/20435546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0901333
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