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Analysis of Naphthalene Adduct Binding Sites in Model Proteins by Tandem Mass Spectrometry

The electrophilic metabolites of the polyaromatic hydrocarbon naphthalene have been shown to bind covalently to proteins and covalent adduct formation correlates with the cytotoxic effects of the chemical in the respiratory system. Although 1,2-naphthalene epoxide, naphthalene diol epoxide, 1,2-naph...

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Bibliografiske detaljer
Main Authors: Pham, Nathalie T., Jewell, William T., Morin, Dexter, Buckpitt, Alan R.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579547/
https://ncbi.nlm.nih.gov/pubmed/22659010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2012.05.009
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