Silica-Based Nanoparticle Uptake and Cellular Response by Primary Microglia

BACKGROUND: Silica nanoparticles (SiNPs) are being formulated for cellular imaging and for nonviral gene delivery in the central nervous system (CNS), but it is unclear what potential effects SiNPs can elicit once they enter the CNS. As the resident macrophages of the CNS, microglia are the cells mo...

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Bibliographic Details
Main Authors: Choi, Judy, Zheng, Qingdong, Katz, Howard E., Guilarte, Tomás R.
Format: Artigo
Language:Inglês
Published: National Institute of Environmental Health Sciences 2010
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866671/
https://ncbi.nlm.nih.gov/pubmed/20439179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0901534
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