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Silica-Based Nanoparticle Uptake and Cellular Response by Primary Microglia

BACKGROUND: Silica nanoparticles (SiNPs) are being formulated for cellular imaging and for nonviral gene delivery in the central nervous system (CNS), but it is unclear what potential effects SiNPs can elicit once they enter the CNS. As the resident macrophages of the CNS, microglia are the cells mo...

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Detalhes bibliográficos
Main Authors: Choi, Judy, Zheng, Qingdong, Katz, Howard E., Guilarte, Tomás R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866671/
https://ncbi.nlm.nih.gov/pubmed/20439179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0901534
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