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Pathogenesis of the Erythroid Failure in Diamond Blackfan Anemia

Diamond Blackfan anemia (DBA) is a severe congenital failure of erythropoiesis. Despite mutations in one of several ribosome protein genes, including RPS19, the cause of the erythroid specificity is still a mystery. We hypothesize that because the chromatin of late erythroid cells becomes condensed...

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Main Authors: Sieff, Colin A., Yang, Jing, Merida-Long, Lilia B., Lodish, Harvey F.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866500/
https://ncbi.nlm.nih.gov/pubmed/19958353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2009.07993.x
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