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Approaches to efficient production of recombinant angiogenesis inhibitor rhVEGI-192 and characterization of its structure and antiangiogenic function

Methods to prepare pure, bioactive recombinant human vascular endothelial growth inhibitor (rhVEGI), a potent inhibitor of angiogenesis potentially applicable in antiangiogenic cancer therapy, are in urgent demand for preclinical investigation as well as future clinical trials of the protein. Here,...

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Detalhes bibliográficos
Main Authors: Chen, Xu, Wu, Jueheng, Liu, Hanning, He, Zhenjian, Gu, Minghui, Wang, Ning, Ma, Jianda, Hu, Jieping, Xia, Lei, He, Haipeng, Yuan, Jie, Li, Jun, Li, Luyuan, Li, Mengfeng, Zhu, Xun
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866271/
https://ncbi.nlm.nih.gov/pubmed/20052682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.323
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