SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway

BACKGROUND AND PURPOSE: The aims of this study were to investigate the anti-cancer activity of SZ-685C, an anthracycline analogue isolated from marine-derived mangrove endophytic fungi, and to explore the molecular mechanisms underlying such activity. EXPERIMENTAL APPROACH: The effect of SZ-685C on...

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Detalhes bibliográficos
Main Authors: Xie, Gui'e, Zhu, Xun, Li, Qing, Gu, Minghui, He, Zhenjian, Wu, Jueheng, Li, Jun, Lin, Yongcheng, Li, Mengfeng, She, Zhigang, Yuan, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828032/
https://ncbi.nlm.nih.gov/pubmed/20128807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00577.x
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