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P2X(1) receptor inhibition and soluble CD39 administration as novel approaches to widen the cardiovascular therapeutic window

Thrombus formation at sites of disrupted atherosclerotic plaques is a leading cause of death and disability worldwide. Although the platelet is now recognized to be a central regulator of thrombus formation, development of antiplatelet reagents that selectively target thrombosis over hemostasis repr...

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Detalhes bibliográficos
Main Authors: Fung, C.Y. Eleanor, Marcus, Aaron J., Broekman, M. Johan, Mahaut-Smith, Martyn P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866184/
https://ncbi.nlm.nih.gov/pubmed/19467446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2009.01.005
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