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Genomic and Epigenetic Instability in Colorectal Cancer Pathogenesis
Colorectal cancer arises as a consequence of the accumulation of genetic alterations (gene mutations, gene amplification, and so on) and epigenetic alterations (aberrant DNA methylation, chromatin modifications, and so on) that transform colonic epithelial cells into colon adenocarcinoma cells. The...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866182/ https://ncbi.nlm.nih.gov/pubmed/18773902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.07.076 |
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