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Genomic and Epigenetic Instability in Colorectal Cancer Pathogenesis
Colorectal cancer arises as a consequence of the accumulation of genetic alterations (gene mutations, gene amplification, and so on) and epigenetic alterations (aberrant DNA methylation, chromatin modifications, and so on) that transform colonic epithelial cells into colon adenocarcinoma cells. The...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866182/ https://ncbi.nlm.nih.gov/pubmed/18773902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.07.076 |
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