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Temporally and spatially controlled expression of transgenes in embryonic and adult tissues

Using ES cell-mediated transgenesis, we generated a novel mouse strain that permits a temporally and spatially controlled expression of responder genes in embryonic and multiple adult tissues. The transgene was constructed in a way that a CMV enhancer linked to the chicken β-actin promoter (CAG) dri...

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Detalhes bibliográficos
Main Authors: Zhang, Qian, Triplett, Aleata A., Harms, Don W., Lin, Wan-chi, Creamer, Bradley A., Rizzino, Angie, Wagner, Kay-Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866092/
https://ncbi.nlm.nih.gov/pubmed/19821046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-009-9329-1
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