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MMPs initiate Schwann cell-mediated MBP degradation and mechanical nociception after nerve damage

Matrix metalloproteinases (MMPs) emerge as modulators of neuropathic pain. Because myelin protects Aβ afferents from ectopic hyperexcitability and nociception from innocuous mechanical stimuli (or mechanical allodynia), we analyzed the role of MMPs in the development of mechanical allodynia through...

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Hlavní autoři: Kobayashi, Hideo, Chattopadhyay, Sharmila, Kato, Kinshi, Dolkas, Jennifer, Kikuchi, Shin-ichi, Myers, Robert R., Shubayev, Veronica I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865888/
https://ncbi.nlm.nih.gov/pubmed/18817874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2008.08.008
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