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MMPs initiate Schwann cell-mediated MBP degradation and mechanical nociception after nerve damage

Matrix metalloproteinases (MMPs) emerge as modulators of neuropathic pain. Because myelin protects Aβ afferents from ectopic hyperexcitability and nociception from innocuous mechanical stimuli (or mechanical allodynia), we analyzed the role of MMPs in the development of mechanical allodynia through...

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Detalhes bibliográficos
Main Authors: Kobayashi, Hideo, Chattopadhyay, Sharmila, Kato, Kinshi, Dolkas, Jennifer, Kikuchi, Shin-ichi, Myers, Robert R., Shubayev, Veronica I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865888/
https://ncbi.nlm.nih.gov/pubmed/18817874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2008.08.008
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