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Human embryonic stem cells: a source of mast cells for the study of allergic and inflammatory diseases

Human mast cells are tissue resident cells with a principal role in allergic disorders. Cross-linking of the high-affinity receptor for immunoglobulin E (FcϵRI) results in release of inflammatory mediators initiating the clinical symptoms of allergy and anaphylaxis. Much of our knowledge regarding t...

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Detalhes bibliográficos
Main Authors: Kovarova, Martina, Latour, Anne M., Chason, Kelly D., Tilley, Stephen L., Koller, Beverly H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865868/
https://ncbi.nlm.nih.gov/pubmed/20200352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-237206
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