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An integer programming formulation to identify the sparse network architecture governing differentiation of embryonic stem cells

Motivation: Primary purpose of modeling gene regulatory networks for developmental process is to reveal pathways governing the cellular differentiation to specific phenotypes. Knowledge of differentiation network will enable generation of desired cell fates by careful alteration of the governing net...

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Autors principals: Banerjee, Ipsita, Maiti, Spandan, Parashurama, Natesh, Yarmush, Martin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865861/
https://ncbi.nlm.nih.gov/pubmed/20363729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq139
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