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An integer programming formulation to identify the sparse network architecture governing differentiation of embryonic stem cells
Motivation: Primary purpose of modeling gene regulatory networks for developmental process is to reveal pathways governing the cellular differentiation to specific phenotypes. Knowledge of differentiation network will enable generation of desired cell fates by careful alteration of the governing net...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865861/ https://ncbi.nlm.nih.gov/pubmed/20363729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq139 |
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