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Reduced Notch Signaling Leads to Renal Cysts and Papillary Microadenomas
The formation of proximal nephron segments requires canonical Notch2 signaling, but other functions of Notch signaling during renal development are incompletely understood. Here, we report that proximal tubules forming with reduced Notch signaling, resulting from delayed conditional inactivation of...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Nephrology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865744/ https://ncbi.nlm.nih.gov/pubmed/20378824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009090925 |
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