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Bioassay for trans-activation using purified human immunodeficiency virus tat-encoded protein: trans-activation requires mRNA synthesis.

Expression of the human immunodeficiency virus tat-encoded protein (Tat) is required for virus replication. A genetic approach was used to facilitate the purification of biologically active Tat. A recombinant Tat protein containing a stretch of six histidine residues and a protease cleavage site was...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Gentz, R, Chen, C H, Rosen, C A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286569/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536934/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.3.821
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