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Inhibitor of hematopoietic pluripotent stem cell proliferation: purification and determination of its structure.

We report here a five-step purification procedure that led to the isolation from fetal calf bone marrow extract of a tetrapeptide, Ac-Ser-Asp-Lys-Pro (Mr 487), exerting a high inhibitory activity on the proliferation of hematopoietic pluripotent stem cells [defined here as spleen colony-forming unit...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Lenfant, M, Wdzieczak-Bakala, J, Guittet, E, Prome, J C, Sotty, D, Frindel, E
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286560/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2915977/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.3.779
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