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The Contribution of HCN4 to Normal Sinus Node Function in Humans and Animal Models

Although sinus node bradycardia is a very common clinical condition, the cellular mechanisms contributing to abnormal sinus node function are not clearly delineated. In recent publications, mutations in the hyperpolarization-activated, cyclic nucleotide-gated (HCN) 4 channels have been associated wi...

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Main Authors: NOF, EYAL, ANTZELEVITCH, CHARLES, GLIKSON, MICHAEL
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865562/
https://ncbi.nlm.nih.gov/pubmed/19796353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1540-8159.2009.02563.x
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