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Rac1 Is Required for Epithelial Stem Cell Function during Dermal and Oral Mucosal Wound Healing but Not for Tissue Homeostasis in Mice

BACKGROUND: The regenerative capacity of the skin, including the continuous replacement of exfoliated cells and healing of injuries relies on the epidermal stem cells and their immediate cell descendants. The relative contribution of the hair follicle stem cells and the interfollicular stem cells to...

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Detalhes bibliográficos
Main Authors: Castilho, Rogerio M., Squarize, Cristiane H., Leelahavanichkul, Kantima, Zheng, Yi, Bugge, Thomas, Gutkind, J. Silvio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865533/
https://ncbi.nlm.nih.gov/pubmed/20463891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010503
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