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Prolonged Antigen Presentation Is Required for Optimal CD8+ T Cell Responses against Malaria Liver Stage Parasites

Immunization with irradiated sporozoites is currently the most effective vaccination strategy against liver stages of malaria parasites, yet the mechanisms underpinning the success of this approach are unknown. Here we show that the complete development of protective CD8+ T cell responses requires p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cockburn, Ian A., Chen, Yun-Chi, Overstreet, Michael G., Lees, Jason R., van Rooijen, Nico, Farber, Donna L., Zavala, Fidel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865532/
https://ncbi.nlm.nih.gov/pubmed/20463809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000877
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