Voltage-gated channels formed in lipid bilayers by a positively charged segment of the Na-channel polypeptide.
The Na-channel polypeptide is responsible for the voltage-gated and time-dependent ionic permeability changes that give rise to the action potential in the membranes of nerve cells. We have synthesized a 22-amino acid peptide with a sequence identical to that of the segment named S4, repeat IV of th...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.2.707 |
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