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Voltage-gated channels formed in lipid bilayers by a positively charged segment of the Na-channel polypeptide.

The Na-channel polypeptide is responsible for the voltage-gated and time-dependent ionic permeability changes that give rise to the action potential in the membranes of nerve cells. We have synthesized a 22-amino acid peptide with a sequence identical to that of the segment named S4, repeat IV of th...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Tosteson, M T, Auld, D S, Tosteson, D C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1989
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286543/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536173/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.2.707
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