Regulation of endocytic pH by the Na+,K+-ATPase in living cells.
Acidification of endocytosed ligands destined for lysosomes is biphasic, with a rapid drop to pH 6, followed by a slow decrease to pH 5. Continuous measurements of transferrin acidification have confirmed that the pH minimum in early (presorting) endosomes is approximately pH 6. On the basis of meas...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1989
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286508/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.2.544 |
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